James Blanchard Selected Research

Zinc Acetate

12/2017	An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques.
7/2015	MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model.
1/2014	A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV.
1/2014	A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants.
8/2013	A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo.
11/2012	A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use.
9/2012	An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaques.
1/2011	An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques.

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James Blanchard Research Topics

Disease

40	Infections 01/2020 - 03/2004
7	HIV Infections (HIV Infection) 07/2019 - 03/2004
7	Sexually Transmitted Diseases (Sexually Transmitted Disease) 11/2018 - 09/2012
6	Viremia 01/2017 - 01/2003
4	Coinfection 01/2017 - 11/2009
3	Herpes Simplex 01/2018 - 02/2014
3	Acquired Immunodeficiency Syndrome (AIDS) 08/2014 - 09/2011
2	Celiac Disease (Celiac Sprue) 01/2018 - 10/2016
2	Skin Neoplasms (Skin Cancer) 01/2008 - 01/2002
1	Anemia 01/2019
1	Syphilis 11/2018
1	Papillomavirus Infections 01/2018
1	Enterocolitis 01/2018
1	Dysbiosis 10/2016
1	Inflammation (Inflammations) 10/2016
1	Diarrhea 06/2016
1	Infectious Pregnancy Complications 01/2016
1	Autoimmune Diseases (Autoimmune Disease) 01/2016
1	Dementia (Dementias) 08/2014
1	Motor Disorders 08/2014
1	Necrosis 02/2014
1	Fibromyalgia (Fibrositis) 10/2012
1	Body Weight (Weight, Body) 04/2011
1	Superinfection 09/2009
1	Virus Diseases (Viral Diseases) 09/2009

Drug/Important Bio-Agent (IBA)

13	MIV 150IBA 12/2017 - 09/2008
10	Anti-Infective Agents (Microbicides)IBA 01/2016 - 11/2009
8	CarrageenanIBA 01/2018 - 11/2012
8	Zinc Acetate FDA Link 12/2017 - 01/2011
6	VaccinesIBA 04/2013 - 03/2004
5	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2017 - 11/2012
4	Antiviral Agents (Antivirals)IBA 12/2017 - 03/2004
3	AntibodiesIBA 01/2018 - 03/2004
3	RNA (Ribonucleic Acid)IBA 01/2017 - 01/2003
3	Reverse Transcriptase InhibitorsIBA 02/2014 - 11/2009
3	Proteins (Proteins, Gene)FDA Link 12/2013 - 03/2004
2	Glutens (Glutelin)IBA 01/2018 - 10/2016
2	Protein Glutamine gamma Glutamyltransferase 2IBA 01/2018 - 06/2016
2	GliadinIBA 01/2018 - 06/2016
2	Contraceptive Agents (Contraceptives)IBA 12/2017 - 01/2016
2	cabotegravirIBA 01/2017 - 01/2015
2	EnzymesIBA 01/2017 - 06/2011
2	IntegrinsIBA 01/2016 - 06/2011
2	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 07/2015 - 11/2014
2	NucleosidesIBA 09/2012 - 11/2009
2	HIV Reverse TranscriptaseIBA 09/2012 - 09/2008
2	Neutralizing AntibodiesIBA 09/2009 - 03/2004
1	Monoclonal AntibodiesIBA 01/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019
1	IronIBA 01/2019
1	Griffithsia griffithsin proteinIBA 01/2018
1	IceIBA 01/2018
1	Immunoglobulin G (IgG)IBA 01/2018
1	Interleukin-15 (Interleukin 15)IBA 01/2018
1	Levonorgestrel (Plan B)FDA LinkGeneric 12/2017
1	ImmunosorbentsIBA 01/2017
1	16S Ribosomal RNAIBA 10/2016
1	MicroRNAs (MicroRNA)IBA 10/2016
1	CaspasesIBA 06/2016
1	Vaccine AdjuvantsIBA 01/2016
1	CD4 Antigens (CD4 Antigen)IBA 08/2014
1	HLA-DR Antigens (HLA-DR)IBA 02/2014
1	Pharmaceutical PreparationsIBA 01/2014
1	N,N-dimethyl-4-anisidine (DMPA)IBA 01/2014
1	Hormones (Hormone)IBA 01/2014
1	AIDS VaccinesIBA 06/2013
1	Indicators and Reagents (Reagents)IBA 01/2013
1	MIV-160IBA 11/2012
1	insulin receptor-related receptor (IRR)IBA 10/2012
1	Vaginal Creams, Foams, and Jellies (Vaginal Tablet)IBA 09/2012
1	Bulk DrugsIBA 09/2012
1	Aldehyde DehydrogenaseIBA 06/2011
1	Rituximab (Mabthera)FDA Link 04/2011
1	CI 22IBA 02/2011
1	ZincIBA 01/2011
1	Designed Ankyrin Repeat ProteinsIBA 08/2010
1	TEMPOIBA 01/2010
1	perillyl alcoholIBA 01/2008
1	DEPOIBA 08/2006
1	cellulose acetate 1,2-benzenedicarboxylateIBA 10/2005
1	Glycerol (Glycerine)FDA LinkGeneric 10/2005
1	Glycoproteins (Glycoprotein)IBA 08/2005
1	Viral ProteinsIBA 08/2005
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 01/2002
1	AntioxidantsIBA 01/2002

Therapy/Procedure

5	Condoms (Condom) 11/2018 - 01/2013
3	Therapeutics 01/2018 - 02/2011
1	Intravenous Administration 01/2020
1	Self-Testing 07/2019
1	Blood Transfusion (Blood Transfusions) 01/2017
1	Gluten-Free Diet 06/2016
1	Resuscitation 01/2016
1	Contraception (Birth Control) 01/2016
1	Chemoprevention 01/2008
1	Thymectomy 01/2005